2025 NFL Week 17 Odds: Updated Lines, Spreads and Totals for All 16 Games

NFL Week 17 begins on Christmas Day with three high-profile matchups, setting the stage for a holiday slate packed with playoff implications across the league.

Below are the betting lines for every Week 17 game, as listed at DraftKings Sportsbook as of December 25.

Week 17 action opens Thursday, December 25, with two games already in the books. Dallas defeated Washington 30–23, resulting in a push on the Cowboys’ seven-point spread, while the total of 50.5 points went over. Earlier in the day, Minnesota handled Detroit 23–10. The Vikings covered as 7.5-point underdogs, and the total of 43.5 points stayed under.

The Christmas night matchup features Denver visiting Kansas City. The Broncos enter as heavy 13.5-point favorites, priced at -1050 on the moneyline, while the Chiefs are listed at +675. The over/under for the game is set at 36.5 points.

Saturday’s slate begins December 27 with Houston traveling to Los Angeles to face the Chargers. The Chargers are favored by 1.5 points, with Houston priced at +110 on the moneyline and Los Angeles at -130. The total for the game sits at 39.5 points.

Later Saturday, Baltimore heads to Green Bay. The Packers are favored by 4.5 points and listed at -205 on the moneyline, while the Ravens come back at +170. The over/under is set at 40.5 points.

Sunday, December 28, features a full day of NFL action beginning with Seattle on the road against Carolina. The Seahawks are seven-point favorites, listed at -375 on the moneyline, while the Panthers are +295. The total is 42.5 points.

New England travels to New York to face the Jets as a commanding 13.5-point favorite. The Patriots are priced at -1000 on the moneyline, with the Jets at +650. The total for the game is 42.5 points.

Pittsburgh visits Cleveland with the Steelers laying three points. Pittsburgh is -180 on the moneyline, while the Browns are +150. The over/under is 34.5 points.

Jacksonville heads to Indianapolis favored by 6.5 points. The Jaguars are listed at -278 on the moneyline, with the Colts at +225. The total is set at 48.5 points.

Arizona travels to Cincinnati, where the Bengals are favored by 7.5 points. Cincinnati is -410 on the moneyline, while the Cardinals are +320. The over/under is 52.5 points.

Tampa Bay faces Miami on the road, laying six points. The Buccaneers are -290 on the moneyline, while the Dolphins are +235. The total sits at 45.5 points.

New Orleans visits Tennessee as a 2.5-point favorite. The Saints are listed at -142 on the moneyline, with the Titans at +120. The over/under is 39.5 points.

The Giants travel to Las Vegas in one of the tightest games of the week. New York is favored by 1.5 points, with the Giants priced at -112 and the Raiders at -108 on the moneyline. The total is 41.5 points.

Philadelphia heads to Buffalo in a matchup with playoff ramifications. The Bills are favored by 1.5 points and listed at -133 on the moneyline, while the Eagles are +102. The over/under is set at 43.5 points.

Chicago visits San Francisco, where the 49ers are three-point favorites. San Francisco is -162 on the moneyline, with the Bears at +136. The total is 52.5 points.

Week 17 concludes Monday, December 29, with the Rams traveling to Atlanta. Los Angeles is favored by 7.5 points and priced at -470 on the moneyline, while the Falcons are +360. The over/under for the game is 49.5 points.

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